diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 067b7005238..9aee7ce0825 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -204,17 +204,6 @@ repos:
           - --passthrough-line-from-input=^pyobjc(.*)$
           - requirements/static/pkg/darwin.in
 
-      - id: pip-tools-compile
-        alias: compile-pkg-windows-3.5-zmq-requirements
-        name: Windows Packaging Py3.5 ZeroMQ Requirements
-        files: ^requirements/((base|zeromq|crypto|windows)\.txt|static/pkg/(windows\.in|py3\.5/windows\.txt))$
-        pass_filenames: false
-        args:
-          - -v
-          - --py-version=3.5
-          - --platform=windows
-          - --include=requirements/windows.txt
-          - requirements/static/pkg/windows.in
 
       - id: pip-tools-compile
         alias: compile-pkg-windows-3.6-zmq-requirements
@@ -667,20 +656,6 @@ repos:
           - requirements/static/ci/crypto.in
 
 
-      - id: pip-tools-compile
-        alias: compile-ci-windows-py3.5-zmq-requirements
-        name: Windows CI Py3.5 ZeroMQ Requirements
-        files: requirements/((base|zeromq|pytest)\.txt|static/((ci|pkg)/(windows|common)\.in|pkg/py3\.5/windows\.txt))$
-        pass_filenames: false
-        args:
-          - -v
-          - --py-version=3.5
-          - --platform=windows
-          - --include=requirements/static/pkg/py{py_version}/windows.txt
-          - --include=requirements/pytest.txt
-          - --include=requirements/static/ci/common.in
-          - requirements/static/ci/windows.in
-
       - id: pip-tools-compile
         alias: compile-ci-windows-py3.6-zmq-requirements
         name: Windows CI Py3.6 ZeroMQ Requirements
diff --git a/noxfile.py b/noxfile.py
index c16070eabe2..575a841faa7 100644
--- a/noxfile.py
+++ b/noxfile.py
@@ -148,6 +148,8 @@ def _get_pydir(session):
     version_info = _get_session_python_version_info(session)
     if version_info < (3, 5):
         session.error("Only Python >= 3.5 is supported")
+    if IS_WINDOWS and version_info < (3, 6):
+        session.error("Only Python >= 3.6 is supported on Windows")
     return "py{}.{}".format(*version_info)
 
 
diff --git a/requirements/static/ci/py3.5/windows.txt b/requirements/static/ci/py3.5/windows.txt
deleted file mode 100644
index dd5a0dd8bda..00000000000
--- a/requirements/static/ci/py3.5/windows.txt
+++ /dev/null
@@ -1,133 +0,0 @@
-#
-# This file is autogenerated by pip-compile
-# To update, run:
-#
-#    pip-compile -o requirements/static/ci/py3.5/windows.txt -v requirements/static/pkg/py3.5/windows.txt requirements/pytest.txt requirements/static/ci/common.in requirements/static/ci/windows.in
-#
-appdirs==1.4.4            # via virtualenv
-atomicwrites==1.3.0       # via pytest
-attrs==20.3.0             # via jsonschema, pytest, pytest-salt-factories
-aws-sam-translator==1.33.0  # via cfn-lint
-aws-xray-sdk==0.95        # via moto
-backports.ssl-match-hostname==3.7.0.1 ; python_version < "3.7"
-boto3==1.13.5
-boto==2.49.0
-botocore==1.16.26         # via boto3, moto, s3transfer
-cachetools==3.1.0         # via google-auth
-cassandra-driver==3.23.0
-certifi==2020.6.20
-cffi==1.12.2
-cfn-lint==0.44.3          # via moto
-chardet==3.0.4
-cheetah3==3.1.0
-cheroot==8.3.0
-cherrypy==17.4.1
-click==7.1.2              # via geomet
-clustershell==1.8.3
-colorama==0.4.1           # via pytest
-contextlib2==0.6.0.post1
-contextvars==2.4 ; python_version < "3.7"
-cryptography==3.0
-decorator==4.4.2          # via networkx
-distlib==0.3.0            # via virtualenv
-distro==1.5.0
-dmidecode==0.9.0
-dnspython==1.16.0
-docker-pycreds==0.4.0     # via docker
-docker==2.7.0
-docutils==0.15.2          # via botocore
-ecdsa==0.13.3             # via moto, python-jose, sshpubkeys
-filelock==3.0.12          # via virtualenv
-flaky==3.7.0
-genshi==0.7.3
-geomet==0.1.2             # via cassandra-driver
-gitdb==4.0.5
-gitpython==3.1.12
-google-auth==1.6.3        # via kubernetes
-idna==2.8
-immutables==0.14
-importlib-metadata==0.23  # via importlib-resources, jsonschema, pluggy, pytest, virtualenv
-importlib-resources==1.5.0  # via cfn-lint, virtualenv
-iniconfig==1.0.1          # via pytest
-ioloop==0.1a0
-ipaddress==1.0.22         # via kubernetes
-jaraco.functools==2.0
-jinja2==2.10.1
-jmespath==0.9.4
-jsondiff==1.2.0           # via moto
-jsonpatch==1.28           # via cfn-lint
-jsonpickle==1.1           # via aws-xray-sdk
-jsonpointer==2.0          # via jsonpatch
-jsonschema==3.2.0
-junit-xml==1.9            # via cfn-lint
-keyring==5.7.1
-kubernetes==3.0.0
-libnacl==1.7.1
-lxml==4.6.2
-mako==1.0.7
-markupsafe==1.1.1
-mock==3.0.5
-more-itertools==8.2.0
-moto==1.3.16
-msgpack==1.0.2
-networkx==2.4             # via cfn-lint
-packaging==19.2           # via pytest
-patch==1.16
-pathlib2==2.3.3           # via pytest
-pathtools==0.1.2          # via watchdog
-pluggy==0.13.0            # via pytest
-portend==2.6
-psutil==5.8.0
-py==1.9.0                 # via pytest
-pyasn1-modules==0.2.4     # via google-auth
-pyasn1==0.4.5
-pycparser==2.19
-pycryptodomex==3.9.8
-pycurl==7.43.0.5
-pygit2==0.28.2 ; python_version < "3.8"
-pymssql==2.1.4 ; python_version < "3.8"
-pymysql==0.9.3
-pyopenssl==19.0.0
-pyparsing==2.4.5          # via packaging
-pyrsistent==0.17.3        # via jsonschema
-pytest-helpers-namespace==2019.1.8
-pytest-salt-factories==0.121.1
-pytest-subtests==0.4.0
-pytest-tempdir==2019.10.12
-pytest==6.1.2
-python-dateutil==2.8.0
-python-etcd==0.4.5
-python-gnupg==0.4.4
-python-jose[cryptography]==3.2.0  # via moto
-pythonnet==2.4.0
-pytz==2020.1
-pyvmomi==6.7.1.2018.12
-pywin32==227
-pyyaml==5.3.1
-pyzmq==18.0.1 ; python_version < "3.8"
-requests==2.21.0
-responses==0.10.6         # via moto
-rfc3987==1.3.8
-rsa==4.0                  # via google-auth, python-jose
-s3transfer==0.3.3         # via boto3
-sed==0.3.1
-setproctitle==1.1.10
-six==1.15.0
-smmap==3.0.4
-sqlparse==0.4.1
-sshpubkeys==3.1.0         # via moto
-strict-rfc3339==0.7
-tempora==1.14.1
-timelib==0.2.5
-toml==0.10.2
-urllib3==1.24.3
-virtualenv==20.0.20
-watchdog==0.10.3
-websocket-client==0.40.0  # via docker, kubernetes
-werkzeug==0.15.6          # via moto
-wheel==0.33.4
-wmi==1.4.9
-wrapt==1.11.1             # via aws-xray-sdk
-xmltodict==0.12.0         # via moto
-zc.lockfile==2.0
-zipp==0.6.0               # via importlib-metadata, importlib-resources, moto
diff --git a/requirements/static/pkg/py3.5/windows.txt b/requirements/static/pkg/py3.5/windows.txt
deleted file mode 100644
index 348703bb92a..00000000000
--- a/requirements/static/pkg/py3.5/windows.txt
+++ /dev/null
@@ -1,55 +0,0 @@
-#
-# This file is autogenerated by pip-compile
-# To update, run:
-#
-#    pip-compile -o requirements/static/pkg/py3.5/windows.txt -v requirements/windows.txt requirements/static/pkg/windows.in
-#
-backports.ssl-match-hostname==3.7.0.1 ; python_version < "3.7"
-certifi==2020.6.20
-cffi==1.12.2
-chardet==3.0.4            # via requests
-cheroot==8.3.0            # via cherrypy
-cherrypy==17.4.1
-contextlib2==0.6.0.post1  # via cherrypy
-contextvars==2.4 ; python_version < "3.7"
-cryptography==3.0
-distro==1.5.0
-gitdb==4.0.5              # via gitpython
-gitpython==3.1.12
-idna==2.8
-immutables==0.14          # via contextvars
-ioloop==0.1a0
-jaraco.functools==2.0     # via cheroot, tempora
-jinja2==2.10.1
-libnacl==1.7.1
-lxml==4.6.2
-mako==1.0.7
-markupsafe==1.1.1
-more-itertools==8.2.0     # via cheroot, cherrypy, jaraco.functools
-msgpack==1.0.2
-portend==2.6              # via cherrypy
-psutil==5.8.0
-pyasn1==0.4.5
-pycparser==2.19
-pycryptodomex==3.9.8
-pycurl==7.43.0.5
-pymssql==2.1.4 ; python_version < "3.8"
-pymysql==0.9.3
-pyopenssl==19.0.0
-python-dateutil==2.8.0
-python-gnupg==0.4.4
-pythonnet==2.4.0
-pytz==2020.1              # via tempora
-pywin32==227
-pyyaml==5.3.1
-pyzmq==18.0.1 ; python_version < "3.8"
-requests==2.21.0
-setproctitle==1.1.10
-six==1.15.0               # via cheroot, cherrypy, cryptography, pyopenssl, python-dateutil, tempora
-smmap==3.0.4              # via gitdb
-tempora==1.14.1           # via portend
-timelib==0.2.5
-urllib3==1.24.3           # via requests
-wheel==0.33.4
-wmi==1.4.9
-zc.lockfile==2.0          # via cherrypy